Hore chefo e bolaeang likokonyana e baka lihlahala joale ho bonahala e se e thehiloe. Eseng feela glyphosate ka mefuta eohle e amahanngoa le ho qala ha mofetše, kapa boikemisetso chefo e bolaeang likokonyana e kotsing e kholo ea mofetše oa bongoana ea tsamaiso ea methapo e bohareng, joale ho bonahala ho hlakile hore ho pepesetsoa lijo ka chefo e bolaeang likokonyana ho ka lebisa ho mofets'e oa matsoele oa postmenopausal.
Sena ke sona se hlahang ho e le 'ngoe Studio Sefora se etelletsoeng pele ke sehlopha sa bafuputsi ba CNAM, INSERM le INRAE mme se phatlalalitsoe hoInternational Journal of Epidemiology, ho hlahloba kamano pakeng tsa ho pepesehela phepo ea meriana e bolaeang likokonyana le kotsi ea ho ba le mofetše oa matsoele ho basali ba postmenopausal ba sehlopha sa projeke ea NutriNet-Santé.
Phuputso e ne e kenyelletsa basali ba 13.149 169 ba postmenopausal, ho kenyeletsoa linyeoe tse 25 tsa mofetše. Bafuputsi ba ile ba lekanya ho pepesehela lintho tse XNUMX tse mafolofolo ha ho etsoa meriana e bolaeang likokonyana e lumelloang Europe, ho qala ka tse sebelisoang temong ea manyolo.
Ebile, ho ea ka lipatlisiso, ho belaeloa hore chefo e bolaeang likokonyana e sebelisitsoeng Europe e na le litlamorao tse mpe bophelong ba motho: li baka mathata a lihormone hape li na le thepa ea kankere. Khokahano lipakeng tsa ho pepesehela meriana e bolaeang likokonyana ka lijo le mofets'e oa matsoele sechabeng ka kakaretso e ntse e sa rutoe hantle. Bafuputsi ba ne ba se ba bontšitse hore bareki ba lijo tse lenngoeng ka tlhaho sehlopheng sa NutriNet-Santé ba na le kotsi e tlase ea mofetše oa postmenopausal. Sehlopha sona sena se ile sa ntšetsa pele mosebetsi oa sona, lekhetlong lena se tsepamisitse maikutlo ho pepeseng li-cocktails tse fapaneng tsa chefo e bolaeang likokoanyana sehlopheng sena sa baahi.
Thuto
Phuputso e ncha ea lilemo tse 'ne e qalile ka 2014. Barupeluoa ba phethile lenane la lipotso ho lekola ts'ebeliso ea lijo tsa tlhaho le tse tloaelehileng. Kakaretso ea basali ba 13.149 ba postmenopausal ba kenyelelitsoe tlhahlobisong mme linyeoe tse 169 tsa mofetše li tlalehiloe.
Mokgwa o tsebahalang ka hore ke "Non-Negative Matrix Factorization" (NMF) o re dumeletse ho theha diprofaele tse nne tsa kgahlamelo ya dikokonyana, tse bontshang metswako e fapaneng ya meriana e bolayang dikokonyana eo re pepesetswang ho yona ka dijo. Joale, lipalo-palo tsa lipalo-palo li ile tsa sebelisoa ho sekaseka lintlha tsena le ho lekola khokahano e ka bang teng le kotsi ea ho ba le mofetše oa matsoele.
Boemo ba NMF n ° 1 bo khetholloa ka ho pepesehela mefuta e 4 ea chefo e bolaeang likokonyana:
- boqhetse
- imazalil
- malathion
- thiabendazole
Boemong bona, bafuputsi ba hlokomela kotsi e kholo ea mofetše oa matsoele oa postmenopausal basali ba batenya haholo (BMI pakeng tsa 25 le 30) kapa ho feta (BMI> 30). Ka lehlakoreng le leng, boemo ba NMF No. 3 bo khetholloa ka ho pepesehela likokoana-hloko tse ngata tsa maiketsetso le ho fokotseha ha 43% kotsing ea kankere ea matsoele ea postmenopausal. Litlaleho tse ling tse peli tse khethiloeng ke NMF li ne li sa amane le kotsi ea mofetše oa matsoele.
Meriana ee e bolaeang likokonyana e entsoe ka eng?
Il boqhetse e sebelisoa, ho etsa mohlala, ka li-citrus, koro, litholoana tsa lejoe kapa lijalo tsa spinach. L 'imazalil e sebelisoa hape ho lema litholoana tsa litholoana, litapole le peo. The malathion, e neng e sebelisoa ho loants'a likokoanyana tse anyang (hoaba, likokoanyana tse lekanyang), e thibetsoe Fora ho tloha ka 2008 empa e lumelletsoe linaheng tse ling tsa Europe. The thiabendazole e sebelisoa, hara tse ling, poone kapa litapole.
Mekhoa e tlisoang ke mekhatlo ena e ka hokahanngoa le thepa ea chefo ea 'mele ea likokoanyana tse bolaeang likokoana-hloko tsa organophosphate tse bakang tšenyo ea DNA, taolo ea cell apoptosis, liphetoho tsa epigenetic, pherekano ea matšoao a sele, e tlamang li-receptor tsa nyutlelie kapa ho kenella ha khatello ea mali.
Liphetho tsa phuputso ena li bontša khokahano lipakeng tsa lifaele tsa phepelo ea likokoanyana tse bolaeang likokoanyana le ho qala ha mofetše oa matsoele oa postmenopausal. "Empa ho netefatsa lintlha tsena - litsebi li phethela - Ka lehlakoreng le leng, ho bohlokoa ho etsa lithuto tsa liteko ho hlakisa mekhoa e amehang mme, ka lehlakoreng le leng, ho netefatsa liphetho ho batho ba bang".
Mehloli: Koranta ea Machabeng ea Epidemiology / TS'ENYETSO
Bala hape:
- Lithethefatsi tse bolaeang likokonyana li fumanoa haholo litholoana le meroho?
- Likokoanyana tse bolaeang likokonyana: hakanya hore ke litholoana le meroho life tse silafetseng ka ho fetesisa? Boemo ba "leshome le metso e litšila"
- Litholoana le meroho: lihlahisoa tse 12 tse silafalitsoeng ka ho fetisisa ke chefo e bolaeang likokonyana (Dirty dozen 2018)
- Malebela a 5 a ho tlosa meriana e bolaeang likokonyana litholoana le meroho
