Iyo mishonga yezvipembenene inokonzeresa mamota ikozvino inoita kunge yakagadzwa. Kwete chete iyo glyphosate mune ese mafomu inosanganiswa nekutanga kwegomarara, kana kutsunga mishonga yekuuraya zvipuka kune njodzi yakawedzera yekenza dzevacheche yeiyo central system yetsinga, ikozvino zvinoita sezviri pachena kuti kuratidzwa kuburikidza nechikafu kumamwe mishonga yekuuraya zvipuka kunogona zvakare kutungamira kune postmenopausal kenza yemazamu.
Ndozvinobuda mune imwe Studio French inotungamirwa neboka revanoongorora kubva kuCNAM, INSERM uye INRAE uye yakaburitswa muInternational Journal of Epidemiology, kuongorora kubatana kuri pakati pekudya kune mishonga yekuuraya zvipuka uye njodzi yekuva nekenza yemazamu mumadzimai ekumiraopaopausal eboka reboka reNutriNet-Santé.
Chidzidzo ichi chaisanganisira vakadzi vanosvika gumi nematanhatu nemakumi mana nevasere vanoguma kuenda kumwedzi, kusanganisira mazana 13.149 emakenza. Vatsvagiri vakayera kuratidzwa kwezvinhu makumi maviri neshanu zvinoshanda mukuumbwa kwemishonga inouraya zvipembenene Europe, kutanga neaya anoshandiswa pakurima makemikari.
Muchokwadi, zvinofungidzirwa, sekutsvaga, kuti mimwe mishonga inouraya zvipembenene inoshandiswa muEurope ine zvinokuvadza pahutano hwevanhu: zvinokonzeresa kusagadzikana kwehomoni uye zvakare zvine carcinogenic zvimiro. Kubatana pakati pekuratidzirwa nemishonga yekuuraya zvipuka kuburikidza nechikafu uye kenza yemazamu muhuwandu hwevanhu kuchiri kudzidza zvisina tsarukano. Vatsvagiri vaive vatoratidza kuti vatengi vezvikafu zvakagadzirwa zvine hutano muboka reNutriNet-Santé vaive nenjodzi yakaderera yekenza yekumira kwemwedzi. Chikwata chimwe chete ichi chakaramba chichienderera nebasa razvo, panguva ino chakanangana nekuratidzwa kune akasiyana mapeche emushonga wezvipembenene munharaunda iyi yevanhu.
Kudzidza
Chidzidzo chitsva chemakore mana chakatanga mu2014.Vatori vechikamu vakapedzisa bvunzo remibvunzo kuti vaongorore kudyiwa kwezvakagadzirwa uye zvakajairwa chikafu. Hwerengedzo ye13.149 vakadzi postmenopausal vakadzi vakaverengerwa mukuwongorora uye 169 kesi dzekenza dzakataurwa.
Maitiro anozivikanwa se "Non-Negative Matrix Factorization" (NMF) akatibvumidza isu kumisikidza maprofayiri ekuratidzira mishonga inouraya, ayo anoratidza misiyano yemishonga yezvipembenene iyo yatinooneswa kuburikidza nechikafu. Zvakare, zviverengero zvemhando zvakashandiswa kuongorora aya ma profiles uye kuongorora iyo ingangoita chinongedzo nenjodzi yekuva nekenza yemazamu.
Iyo NMF nhoroondo n ° 1 inoratidzirwa nekuratidzwa kwakakwira kune mana marudzi emishonga yekuuraya zvipuka.
- chlorpyrifos
- imazalil
- malathion
- thiabendazole
Mune chimiro ichi, vaongorori vanocherekedza njodzi yakawedzera yekenza yemazamu inonzi postmenopausal vakadzi vakawandisa (BMI pakati pe25 ne30) kana obese (BMI> 30). Mukupesana, iyo NMF No. Iwo mamwe ma profiles maviri akaonekwa neNMF anga asingabatanidzwe nenjodzi yekenza yemazamu.
Ndezvipi izvi mishonga yekuuraya zvipuka?
Il chlorpyrifos inoshandiswa, semuenzaniso, pane macitrus, gorosi, michero yematombo kana sipinashi zvirimwa. L 'imazalil inoshandiswawo kurima michero yemichero, mbatatisi uye mbeu. Iyo malathion, yakashandiswa kurwisa zvipembenene zvinoyamwa (aphid, scale scale) zvakarambidzwa muFrance kubvira 2008 asi zvakapihwa mvumo mune dzimwe nyika dzeEurope. Iyo thiabendazole inoshandiswa, pakati pezvimwe zvinhu, pachibage kana mbatatisi.
Maitiro ari pasi pemasangano aya anogona kusunganidzwa necocinogenic zvimiro zveimwe organophosphate mishonga yekuuraya zvipuka inokanganisa kukuvara kweDNA, kudzikiswa kwesero apoptosis, epigenetic moditions, kukanganiswa kwemasaini esero, kusunga kune anogamuchira nyukireya kana kuiswa kweiyo oxidative kusagadzikana.
Mhedzisiro yenyaya iyi inoratidza kubatana pakati pemamwe mapiritsi ekuratidzira zvipembenene uye kutanga kwekenza yemazamu inonzi postmenopausal. "Asi kusimbisa idzi data - nyanzvi dzinopedzisa - Kune rimwe divi, zvakakosha kuitisa zvidzidzo zvekuyedza kujekesa nzira dzakabatanidzwa uye, kune rimwe divi, kuratidza izvi mhedzisiro mune vamwe vanhu.".
Zvinyorwa: International Zvinyorwa zve Epidemiology / KUSVIRA
Verenga zvakare:
- Ndezvipi mishonga yekuuraya zvipuka inowanikwa zvakanyanya mumichero nemiriwo?
- Mishonga inouraya zvipembenene: fungidzira kuti ndeapi michero nemiriwo zvakasvibiswa zvakanyanya? Iyo "yakasviba gumi nemaviri" chinzvimbo
- Zvibereko nemiriwo: zvigadzirwa gumi nembiri zvakashatiswa zvakanyanya nemishonga yezvipembenene (Zvakasviba gumi nemaviri 12)
- Matipi mashanu ekubvisa mishonga yekuuraya zvipuka kubva kumichero nemiriwo
