Hoʻomaʻalohi ʻo Omega-3 i ka holomua o kekahi mau maʻi ʻōpū malignant: ka loaʻa, ka hana a kahi hui noiʻi oKulanui o Leuven, hōʻoia i kekahi o nā noiʻi maʻi ʻaʻai ma mua a wehe i ka puka i nā hanana kūpono hou.
ʻO nā waiwai kūpono o nā mea i kapa ʻia ʻo "nā momona momona maikaʻi", pono no ke olakino kanaka a ʻimi nui ʻia e ka poʻe e ʻimi ana e ʻai i ke olakino, ua ʻike mua ʻia. Ma waena o nā waikawa momona Omega-3, pono ka docosahexaenoic acid (DHA) no ka hana o ka lolo, ka hihiʻo a me ke kaohi o nā phenomena hoʻonāukiuki.
Heluhelu pū kekahi: Omega 3: nā keu pono āpau o nā momona "maikaʻi"
Ua hōʻike ʻia kahi noiʻi mua i kahi kuleana i ka pale a me ka hoʻolōʻihi ʻana i ka holomua o kekahi ʻano maʻi ʻaʻai, me ka umauma a me ke kolona.
Heluhelu pū kekahi: Omega 3 e hakakā i ka maʻi ʻaʻai umauma
Heluhelu pū kekahi: Ka maʻi ʻaʻai kolona: ʻo ka aila cod waiwa kahiko e pale aku iā ia?
I ka 2016, alakaʻi ʻia ka hui Leuven e ʻO Olivier Feron, ka mea loea i ka oncology, ua ʻike ʻo nā hunaola maʻi ʻaʻai i loko o kahi microen environment acidic e pani i ka glucose me nā lipids ma ke ʻano he ikehu e hoʻonui. I ka makahiki 2020, ua hōʻike kahi hoa hana i kēia mau pūnaewele like ʻoi loa ka ikaika a loaʻa ka hiki ke haʻalele i ka tumo kumu e hana i nā metastases.
I kēia manawa, kekahi kime mai ke kulanui like, ʻoiai ke hoʻomohala nei i nā kumuwaiwai maikaʻi o nā lipidʻai, i noi ʻia e loiloi i ke ʻano o nā hunaola maʻi ʻi i ke alo o nā waikawa momona like ʻole.
No laila ua hoʻomaopopo koke ka hui i nā ʻikena maʻi ʻaʻai acidotic i pane i ka diametrically ma ke ala ʻē aʻe e pili ana i ka momona momona a lākou e omo ai, a i loko o kekahi mau pule, mahalo a pīhoihoi nā hopena.
Ua ʻike koke mākou ua hōʻeuʻeu kekahi mau momona momona i nā hunaola maʻi ʻino a ʻo kekahi poʻe i pepehi iā lākou
wehewehe i ka poʻe noiʻi.
Ma ka kikoʻī, ka DHA li mea ʻawaʻawa maoli. Hana kēia lāʻau make i nā hunaola maʻi ʻaʻai ma o kahi hanana i kāhea ʻia ferroptosis, kahi ʻano make cell i pili i ka peroxidation o kekahi mau waikawa momona. ʻO ka nui o nā waikawa unsaturated fatty acid i loko o ke keʻena, ʻo ka nui o ka makaʻu o kā lākou hana hoʻoliʻiliʻi.
© Kulanui o Leuven
ʻO ka maʻamau, i loko o ka lumi acid i loko o nā tumors, mālama nā hunaola i kēia mau waiʻona momona i loko o nā droplets lipid, kahi ʻano pūʻulu kahi e pale ʻia ai nā waikawa momona mai ka hoʻowali ʻia. Akā, i ke alo o kahi nui o DHA, ua uhi ʻia ka pūnaeho maʻi ʻaʻai a ʻaʻole hiki ke mālama iā DHA, kahi e hoʻoliʻiliʻi a hiki i ka make.
Ke hoʻohana nei i kahi mea hoʻopili lipid metabolism e pale ai i ka hoʻokumu ʻana o ka lipid droplet, ua ʻike nā mea noiʻi ua hoʻonui hou ʻia kēia hanana, kahi e hōʻoia ai i ka hana i hōʻike ʻia a wehe i ka puka i nā mea hiki. o ka lapaʻau hoʻohui ʻia.
No kā lākou noiʻi, ua hoʻohana nā mea noiʻi i kahi ʻōnaehana moʻomeheu kiko 3D tumo, nā spheroids, e hōʻike ana i kahi hoʻohālikelike hoʻokolohua waena ma waena o nā moʻomeheu a me nā tumors i loko o vivo a e ulu ana i ka vitro, hiki i nā ʻano like ʻole.
Ua hōʻike nā ʻepekema, i ke alo o DHA, ua ulu mua nā spheroids a laila imploded, e hōʻoia ana i kēlā ua hoʻolohi nui ʻia ka hoʻomohala ʻōiwi.
© Kulanui o Leuven
I kēia manawa he hana keʻena hoʻokolohua, e hōʻoia ana i nā noiʻi ʻē aʻe i hala.
A me nā hopena "kūpono"?
No kahi mākua - wehewehe ka poʻe noiʻi - koi ʻia ia e hoʻopau ma ka liʻiliʻi 250 mg o DHA i kēlā me kēia lā. Akā hōʻike nā haʻawina e hāʻawi wale kā mākou papaʻai i 50 i ka 100 mg i kēlā me kēia lā ma ka awelika. ʻOi loa kēia ma lalo o ka palena iki e pono ai ka ʻai.
ʻAʻole e kū ke kime, e kuhikuhi ana iā DHA ma ke ʻano he kī i nā koho koho maʻi ʻaʻai ʻē aʻe, ʻoi aku ka maikaʻi a emi paha ka invasive.
Ua paʻi ʻia ka hana ma ʻO ka pūnaewele kāpili.
Nā Kumuwaiwai o ke kūmole: Kulanui o Leuven / ʻO ka pūnaewele kāpili
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