Mgwirizano wa caffeine pakhungu, motsutsana ndi khansa ya pakhungu. Kafukufuku watsopano, wochitidwa ndi Istituto Superiore di Sanità ndi mayunivesite ena aku Italiya, apeza zomwe zitha kupindulitsa khofiine kudzera pakukula kwa melanin
Malinga ndi kusanthula kwatsopano, chinthu ichi chomwe chili mu khofi chimakhala ndi chitetezo chowonekera pakukula kwamaselo khansa, chotupa chakhungu chakhungu. Awa ndi malingaliro omwe akatswiri ofufuza a ISS adachita mogwirizana ndi anzawo a IRCCS awiri (IDI yaku Roma ndi Neuromed ya Pozzilli) komanso mayunivesite awiri aku Italy (University of Ferrara ndi University of Rome "Tor Vergata"). Ngongole ndi ya enzyme, yotchedwa kachulu.
Kuwunikaku, komwe kunalembedwa munyuzipepala yapadziko lonse ya Molecules, kunafuna kudziwa njira zomwe caffeine imagwira ntchito yofunika yoteteza ku mitundu ina ya khansa. Mfundo yomwe aphunzira kale kale ndi asayansi ena koma osamveketsa pamlingo wamaselo.
Pogwiritsa ntchito njira za silico ndi in vitro, tazindikira puloteni yomwe mwina imagwira ntchito yofunika kwambiri pakafeine, yomwe ndi enzyme kachulu yomwe, monga tikudziwira, imakhala ndi ntchito yayikulu pakapangidwe ka melanin ndipo imatha kuteteza ndi kuwonongeka komwe kumachitika ndi cheza cha UV, komanso ntchito yofunika yoteteza chitetezo cha mthupi. M'malo mwake, khansa ya melanin yomwe imapangidwa ndi maselo a khansa ya khansa yomwe imapezeka ndi caffeine idakulitsidwa kwambiri,
anafotokoza Dr. Francesco Facchiano, wotsogolera kafukufukuyu ku Dipatimenti ya Oncology ndi Molecular Medicine ya ISS.
Kusankhidwa kwamitundu yamagetsi kunali kofunikira kwambiri, komwe mu kafukufukuyu ndi 'maselo oyambitsa khansa ya khansa' omwe ali ndi mawonekedwe osangalatsa, kuphatikizapo kuthekera kokana mankhwala osokoneza bongo komanso kubwerezanso chotupa: caffeine yachepetsa kwambiri kukula kwa ma cell . Tidawunikiranso gawo lomwe ma molekyulu azizindikiro monga IL-1β, IP-10, MIP-1cy, MIP-1β ndi RANTES, omwe katulutsidwe kake ndimaselo otukukawa amachepetsedwa akapezeka ndi caffeine.
akutsindika dr. Claudio Tabolacci, wolemba woyamba pankhaniyi komanso wofufuza wothandizidwa ndi Umberto Veronesi Foundation.
Izi sizitanthauza kuti tiyenera kumwa khofi wambiri kuti tipeze zabwino zomwe tikufuna. M'malo mwake, tikukumbukira (ndipo olemba kafukufuku amanenanso), kuti caffeine ilinso ndi kuthekera zotsatira zoyipa.
Chowonadi ndichakuti kafukufuku watsopanoyu amatha kupereka chidziwitso chatsopano potengera zomwe amati ndizosiyanitsa, ndiye kuti, cholinga chake ndi kusiyanitsa maselo kuti angolimbana ndi omwe ali ndi khansa okha, kupewa kuwonekeranso pambuyo pa chemo. Imodzi mwa mankhwala osangalatsa kwambiri komanso odalirika pakati pa omwe akuyenera kulimbana ndi zotupa zoyipa monga khansa ya pakhungu.
Werengani nkhani zathu pa tiyi kapena khofi
Zowonjezera: ISS, Mamolekyuli
WERENGANI:
